These six misunderstandings of allergic purpura, how many of you have recruited?
Purple sputum will have skin purple spots, which will cause kidney damage. Many people have deep misunderstandings about allergic purpura. Let’s take a look at the six misunderstandings of allergic purpura. See if you have recruited?
Misunderstanding of six major misunderstandings of allergic purpura 1: Is hemorrhagic rash a coagulopathy?
In patients with allergic purpura (HSP), the platelet count is normal or elevated, and the coagulation function is basically normal or even hyperthyroidism.
This is because the abnormal reaction of the body’s immune system leads to increased fragility and permeability of the capillaries, extravasation of the blood, skin purpura, bleeding of the mucous membranes and certain organs.
Therefore, although it is a hemorrhagic rash, it is necessary to use anticoagulant drugs properly during treatment.
Myth 2: Is the cause of allergic purpura “allergic”?
HSP is not an allergic disease such as hypertension, acute measles, etc., and its essence is systemic IgA-associated small vasculitis.
The cause is still unclear, allergies can be used as an incentive, such as: fish, shrimp and other food allergies, prevention and prevention, insect bites and drug allergies.
Common causes are: bacteria, viruses, parasitic infections, genetic susceptibility, certain malignant diseases, anti-tumor drugs such as cytarabine, and even weather changes.
Myth #3: Is the more rash the more serious?
The bleeding on the surface is not terrible. It is easy to be found and can be paid enough attention. It is characterized by a symmetrical hemorrhagic rash, which does not fade, and the rash is clearly defined or fused into a piece. The skin biopsy shows IgA immune complex deposition, which is easy to diagnose.
The bleeding of internal organs is more insidious, often manifested as abdominal pain, vomiting, bloody stools, microscopic hematuria, if not accompanied by a rash, it is easy to be misdiagnosed.
Myth 4: The more difficult it is to cure the pathological grade of purpuric nephritis?
The pathological grade was grade I to VI, further subdivided into focal/segmental, b diffuse interference (I, class VI is not grouped), general IIa to IIIa, IVa, Va, IIb to IIIb, IVb, Vb.
First, the focal/segment variable group is better than the diffuse variable group.
However, it is necessary to combine the clinical manifestations and tubulointerstitial changes to more accurately diagnose purpuric nephritis, assess the degree of involvement and efficacy, and determine the prognosis.
Myth 5: Is there normal “arrow, +” in urine?
HSP has a certain self-limiting nature, and the general prognosis is good.
About 40% of patients progress to purpuric nephritis (HSPN) 4-6 weeks after the onset of symptoms, of which 1%-3% can progress to chronic renal insufficiency to end-stage renal failure.
HSPN has different clinical manifestations, which may be temporary hematuria and/or proteinuria, or it may be manifested as obvious kidney damage such as nephritis or nephrotic syndrome.
Therefore, the diagnosis and even suspected HSP should be routinely checked for urine at the onset of illness.
The urine routine test list should first check whether the specimen is qualified. The urine specimen with low urine specific gravity is a substitute specimen. It is impossible to judge whether it is normal or not. It is necessary to check the urine protein/creatinine at the same time, or leave the morning urine for judgment.
Myth 6: Does HSP not follow the rash without a rash?
Patients with a negative urine test during the course of HSP should be monitored for at least 6 months, once a week, and the time to start is the last time a new rash occurs.
If there is an abnormal urine test during the course of the disease, the extension time should be extended, at least 3?